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Norzoanthamine

Norzoanthamine

IUPAC name	(4aS,6aS,7S,7aS,9aS,11S,13R,15aR,16aS,16bR)-1,4a,5,7,7a,8,9,11,12,13,14,16,16a,16b-Tetradecahydro-2,7,7a,11,16a-pentamethyl-4H,10H-9a,13-epoxy-15a,7-(epoxyethano)azepino[1,2-a]naphtho[2,1-g]quinoline-4,6,18(6aH)-trione
Other names	Norzoanthamine
Identifiers
CAS number	164991-65-5
Properties
Molecular formula	C₂₉H₃₉NO₅
Molar mass	481.62
Except where noted otherwise, data are given for materials in their standard state (at 25 °C, 100 kPa) Infobox disclaimer and references

Norzoanthamine is a new alkaloid found in Zoanthus species (Class Anthozoa), a kind of sea anemones.

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Norzoanthamine has been shown to suppress the loss of bone weight and strength in mice; that could lead to a treatment for osteoporosis. Some derivatives of norzoanthamine also suppress development of some kind of leukemia cell lines and human platelet aggregation.

A laboratory synthesis of this compound was developed in 2004.^[1]

References

^ Masaaki Miyashita, Minoru Sasaki, Izumi Hattori, Mio Sakai, Keiji Tanino. "Total Synthesis of Norzoanthamine" Science 23 July 2004: Vol. 305. no. 5683, pp. 495 - 499 doi:10.1126/science.1098851

Categories: Alkaloids | Lactones