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Systematic (IUPAC) name
3-(2-Diethylamino-ethyl)-1H-indol-4-yl acetate
CAS number  ?
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PubChem  ?
Chemical data
Formula C16H22N2O2 
Mol. mass 273.36 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
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Therapeutic considerations
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Legal status
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4-Acetoxy-DET (4-Acetoxy-N,N-diethyltryptamine), also known as ethacetin, ethylacybin or 4-AcO-DET is a hallucinogenic tryptamine. It was first synthesized in 1958 by Albert Hofmann in the Sandoz lab.[1]

Within the body a percentage may be partially hydrolized into the free phenol 4-HO-DET. Human studies concerning the metabolic fate of this drug are lacking.


4-Acetoxy-DET is orally active, and dosages of 10-25 mg are common. Effects last 4-6 hours.[2] The free base is also active when smoked in a dose range of 5-20 mg.[1] Smoking 4-acetoxy-DET greatly speeds up the onset; peak effects are experienced within 10 minutes, and are usually over within 1 hour.[specify]


4-Acetoxy-DET is unscheduled in the United States, but possession and sales of 4-Acetoxy-DET could be prosecuted under the Federal Analog Act because of its structural similarities to DET.


  1. ^ a b Erowid 4-Acetoxy-DET Vaults : Primer. Accessed on April 19, 2007.
  2. ^ Tikhal: The Chemistry Continues by Alexander and Ann Shulgin. #16. 4-HO-DET. Accessed on April 19, 2007.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "4-Acetoxy-DET". A list of authors is available in Wikipedia.
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