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7SL RNA is an RNA molecule, component of the signal recognition particle (SRP).

Although originally the SRP was thought to be only composed by 6 polypeptides, this small cytoplasmic RNA molecule was found to be a component of the complex.

The RNA gene for 7SL is transcribed by the RNA polymerase III.

The common SINE family Alu probably originated from a duplication of a 7SL RNA gene.

See also

  • Eukaryotic type signal recognition particle RNA
  • Bacterial signal recognition particle RNA


  • Walter P, Blobel G. "Signal recognition particle contains a 7S RNA essential for protein translocation across the endoplasmic reticulum.", Nature 21;299(5885):691-8 (1982).
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "7SL_RNA". A list of authors is available in Wikipedia.
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