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AD-mix in organic chemistry is a commercially available mixture of reagents for performing amongst others the Sharpless asymmetric dihydroxylation of alkenes. The mix is available in two variations, "AD-mix α" and "AD-mix β" following ingredient lists published by Sharpless.[1] As such it is used in research laboratories.

The mixes contain:

In AD-mix α (DHQ)2PHAL (top) is the phthalazine adduct with dihydroquinine.

In AD-mix β; (DHQD)2PHAL is the phthalazine adduct with dihydroquinidine.

See also


  1. ^ ^  Sharpless, K. B., et al. J. Org. Chem. 1992, 57, 2768-2771. (doi:10.1021/jo00036a003)
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "AD-mix". A list of authors is available in Wikipedia.
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