Actin-binding protein

Actin-binding proteins are proteins that bind to actin. This may mean ability to bind actin monomers, or polymers, or both.

Many actin-binding proteins, including a-actinin, ß-spectrin, dystrophin, utrophin and fimbrin, do this through the actin-binding calponin homology domain.

This is a list of actin-binding proteins in alphabetical order.

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0–9

• 25kDa
• 25kDa ABP from aorta p185neu
• 30akDA 110 kD dimer ABP
• 30bkDa 110 kD (Drebrin)
• 34kDA
• 45kDa
• p53
• p58gag ^[1]
• p116rip

A

• a-actinin
• Abl
• AbLIM Actin-Interacting MAPKKK
• ABP120
• ABP140
• Abp1p
• ABP280 (Filamin)
• ABP50 (EF-1a)
• Acan 125 (Carmil)
• ActA
• Actibind
• Actin
• Actinfilin
• Actinogelin
• Actin-regulating kinases
• Actin-Related Proteins
• Actobindin
• Actolinkin
• Actopaxin
• Actophorin
• Actup
• Adducin
• ADF/Cofilin
• Adseverin (scinderin)
• Afadin
• AFAP-110
• Affixin
• Aginactin
• AIP1
• Aldolase
• Angiogenin
• Anilin
• Annexins
• Aplyronine
• Archvillin
• Arginine Kinase
• Arp2/3 complex

B

• Band 4.1
• Band 4.9(Dematin)
• b-actinin
• b-Cap73
• Bifocal
• Bistramide A
• BPAG1
• Brevin (Gelsolin)

C

• c-Abl
• Calpactin (Annexin)
• CHO1
• Cortactin
• CamKinase II
• Calponin
• Chondramide
• Cortexillin
• CAP
• Caltropin
• CH-ILKBP
• CPb3
• Cap100
• Calvasculin
• Ciboulot
• Coactosin
• CAP23
• CARMIL
• Acan125
• Cingulin
• Cytovillin (Ezrin)
• CapZ/Capping Protein
• a-Catenin
• Cofilin
• CR16
• Caldesmon
• CCT
• Comitin
• Cytochalasins
• Calicin
• Centuarin
• Coronin

D

• DBP40
• Drebrin
• Dematin (Band 4.9)
• Dynacortin
• Destrin (ADF/cofilin)
• Dystonins
• Diaphanous
• Dystroglycan
• DNase I
• Dystrophin
• Doliculide
• Dolastatins

E

• EAST
• Endossin
• EF-1a (ABP50)
• Eps15
• EF-1b
• EPLIN
• EF-2
• Epsin
• EGF receptor
• ERK
• ENC-1
• ERM proteins (ezrin, radixin, moesin, plus merlin)
• END3p
• Ezrin (the E of ERM proteins)

F

• F17R
• Fodrin (spectrin)
• Fascin
• Formins
• Fessilin
• Frabin
• FHL3
• Fragmin
• Fhos
• Filamin
• Fimbrin (plastin)

G

• GAP43
• Glycogenins
• Gas2
• G-proteins
• Gastrin-Binding Protein
• Gelactins I-IV
• Gelsolins
• Glucokinase

H

• Harmonin b
• Hrp36
• Hexokinase
• Hrp65-2
• Hectochlorin
• HS1 (actin binding protein)
• Helicase II
• Hsp27
• HIP1 (Huntingtin Interacting protein 1)
• Hsp70
• Histactophilin
• Hsp90
• Histidine rich protein II
• Hsp100

I

• Inhibitor of apoptosis (IAP)
• Insertin
• Interaptin
• IP3Kinase A (Inositol 1,4,5-trisphosphate 3-kinase A)
• IQGAP
• Integrins

J

• Jaspisamide A
• Jasplakinolide

K

• Kabiramide C
• Kaptin
• Kettin
• Kelch protein

L

• Latrunculin L2
• 5-Lipoxygenase
• Limatin
• Lim Kinases
• Lim Proteins
• L-plastin
• Lymphocyte Specific Protein 1 (LSP1)

M

• MacMARKS
• Mena
• Myopodin
• MAP-1A
• Merlin (related to the ERM proteins)
• Myosins
• MAP-1C
• Metavinculin
• Moesin (the M of ERM proteins)
• Myosin Light Chain Kinase
• MAL
• Mip-90
• Myosin Light Chain A1
• MARKS
• MIM
• MAYP
• Mycalolide (a macroglide drug)
• Mayven
• Myelin basic protein

N

• Naphthylphthalamic acid binding protein (NPA) N-RAP
• Nebulin
• N-WASP
• Neurabin
• Nullo
• Neurexins
• Neurocalcin
• Nexillin
• Neurabin

O

• OYE2

P

• Palladin
• Plastin
• p30
• PAK (p21-activated Kinase)
• Plectin
• p47PHOX
• Parvin (actopaxin)
• Prefoldin
• p53
• PASK (Proline, Alanine rich Ste20 related Kinase)
• Presenilin I
• p58
• Phalloidin
• Profilin
• p185neu
• Ponticulin
• Protein kinase C
• Porin
• P.IB
• Prk1p (actin regulating kinase)

R

• Radixin (the R of ERM proteins)
• Rapsyn
• Rhizopodin
• RPL45
• RTX toxin (Vibrio cholerae)
• RVS 167

S

• Sac6
• Sla1p
• Srv2 (CAP)
• S-Adenosyl-L-homocyteine hydrolase, (SAHH)
• Sla2p
• Synaptopodin
• Scinderin (adseverin)
• Synapsins
• Scruin
• Spectrin
• Severin
• Spectraplakins
• SVSII
• Shot (Short stop)
• Spire
• Shroom
• Smitin (Smooth Musc.Titin)
• Supervillin
• SipA
• Smoothelin
• Sucrose synthetase
• SipC
• Sra-1
• Spinophilin
• Ssk2p
• Swinholide

T

• Talin protein
• Toxophilin
• Twinfilin
• Tau
• Trabeculin
• Twinstar
• TCP-1
• Transgelin
• Tensin
• Tropomodulin
• Thymosin
• Tropomyosin
• Titin
• Troponin
• TOR2
• Tubulin bIV

U

• Ulapualide
• Utrophin
• Unc-87
• Unc-60 (ADF/cofilins)

V

• VASP
• Vinculin
• VAV
• Verprolin
• VDAC
• Vibrio cholerae RTX toxin
• Villin
• Vitamin D binding protein

W

• WIP
• WASp

Y

• Y-box proteins
• YpkA (YopO)

Z

• Zipper protein
• Zo-1
• Zyxin

References

Sources consulted

• Maciver, Sutherland, ed. (online). The Encyclopaedia of Actin-Binding Proteins (and Drugs). Maciver Lab Web Page. School of Biomedical Sciences, University of Edinburgh.

Endnotes