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Ascofuranone is an antibiotic produced by the fungus Ascochyta visiae that inhibits the Trypanosoma brucei alternative oxidase and is a lead compound in efforts to produce other drugs targeting this enzyme for the treatment of sleeping sickness. The compound is effective both in vitro cell culture and in infections in mice.
Additional recommended knowledge
Ascofuranone has also been reported to have anti-tumor activity, and modulate the immune system.
Categories: Antibiotics | Terpenes and terpenoids
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ascofuranone". A list of authors is available in Wikipedia.|