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Bouveault-Blanc reduction

The Bouveault-Blanc reduction is a chemical reaction in which an ester is reduced to primary alcohols using absolute ethanol and sodium metal.[1][2][3]

This reaction is an inexpensive and large-scale alternative to lithium aluminum hydride reduction of esters.

Reaction mechanism

Sodium metal is a single-electron reducing agent, meaning the sodium metal will transfer electrons one at a time. Four sodium atoms are required to fully reduce each ester to alcohols. Ethanol serves as a proton source.


  1. ^  Bouveault, L.; Blanc, G. Compt. Rend. 1903, 136, 1676.
  2. ^  Bouveault, L.; Blanc, G. Bull. Soc. Chim. France 1904, 31, 666.
  3. ^  Adkins, H.; Gillespie, R. H. Org. Syn., Coll. Vol. 3, p.671 (1955); Vol. 29, p.80 (1949). (Article)

See also

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Bouveault-Blanc_reduction". A list of authors is available in Wikipedia.
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