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CD200 is a cell surface receptor that acts in transplantation to reject grafts, such as skin grafts

The protein encoded by this gene is a type-1 membrane glycoprotein, which contains two immunoglobulin domains, and thus belongs to the immunoglobulin superfamily. Studies of the related genes in mouse and rat suggest that this gene may regulate myeloid cell activity and delivers an inhibitory signal for the macrophage lineage in diverse tissues. Multiple alternatively spliced transcript variants that encode different isoforms have been found for this gene.

It is currently under research by Dr. Reginald M. Gorcyznski at the University Health Network.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "CD-200". A list of authors is available in Wikipedia.
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