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Cross-linked N-telopeptide of type I collagen

Cross-linked N-telopeptides of type I collagen (NTX or NTx) are a specific breakdown product of the type-I collagen found in bone cartilage, used as a marker of bone turnover. NTx is measured in the urine or serum.

Urine NTX levels of greater than 40 nmol/L indicate excessive bone turnover and is a sign of osteoporosis. Levels less than 14 may indicate over-aggressive treatment of osteoporosis with drugs such as bisphosphonates and can lead to "frozen bone syndrome".

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Cross-linked_N-telopeptide_of_type_I_collagen". A list of authors is available in Wikipedia.
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