Duodenal cytochrome B

Duodenal cytochrome B (Dcytb) has been identified as the reductase enzyme which catalyzes the reduction of Fe³⁺ to Fe²⁺ in the process of iron absorption in the duodenum of mammals.^[1] According to research carried out, it appears that Dcytb upregulation is controlled by a number of independent stimulators or inhibitors of iron absorption. Furthermore, Dcytb has also been shown to exist in other tissues besides the apical region of the duodenum; and as such, it is believed to play a major role in iron metabolism in tissues.

References

1. ^ Latunde-Dada GO, Van der Westhuizen J, Vulpe CD et al (2002). "Molecular and functional roles of duodenal cytochrome B (Dcytb) in iron metabolism". Blood Cells Mol. Dis. 29 (3): 356-60. PMID 12547225.