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Methylecgonidine is produced by pyrolysis in the process of smoking crack cocaine, and then subsequently metabolised to ecgonidine, and so these two compounds can be tested for as a specific biomarker for crack cocaine use. Ecgonidine is formed as a metabolite of methylecgonidine, and so the relative concentrations of the two compounds can be used to gauge how recently crack cocaine was smoked; if levels of methylecgonidine are higher then the drug was smoked recently, however after a longer time period mainly ecgonidine will be present. Ecgonidine has a half-life in the body of around 94-137 minutes, and so can be used to detect use of crack cocaine up to 8-10 hours after the drug is consumed.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Ecgonidine". A list of authors is available in Wikipedia.|