To use all functions of this page, please activate cookies in your browser.
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
In physiology, electrotonic conduction refers to the passive conduction of current, and can be considered the opposite of saltatory conduction. In order for a neuron to fire, there are two types of electrical potentials produced. The first is a non-propagated local potential called an electrotonic potential and the second is a propagated impulse called an action potential. Electrotonic potentials represent changes to the neuron's membrane potential that do not lead to the generation of new current by action potentials. Neurons which are small in relation to their length, such as some neurons in the brain have only electrotonic potentials (starbust amacrine cells in the retina are believed to have these properties); longer neurons utilize electrotonic potentials to trigger the action potential.
Additional recommended knowledge
The electrotonic potential travels via electrotonic spread, which amounts to simple diffusion of the ions down their electrochemical gradient within the cell. If sodium ions enter via a single channel in a dendrite, they are in higher concentration at that location and therefore spread out into the lower concentration areas, bringing with them their positive charge. Electrotonic potentials can sum spatially or temporally. Spatial summation is the combination of multiple sources of ion influx (multiple channels within a dendrite, or channels within multiple dendrites), where temporal summation is a gradual increase in overall charge due to repeated influxes in the same location. Because the ionic charge enters in one location and dissipates to others, losing intensity as it spreads, electrotonic spread is a graded response. It is important to contrast this with the all-or-none propagation of the action potential down the axon of the neuron.
Electrotonic spread is generally responsible for increasing the voltage of the soma (neuronal cell body) sufficiently to exceed threshold and trigger the action potential; its summation properties described above make it suitable for integrating input from many different sources. Such input may be depolarizing (positive charge, such as sodium) or hyperpolarizing (negative charge, such as chloride).
Electrotonic potentials are conducted faster than action potentials, but attenuate rapidly so are unsuitable for long-distance signaling.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Electrotonic_potential". A list of authors is available in Wikipedia.|