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Systematic (IUPAC) name
CAS number 142217-69-4
ATC code J05AF10
PubChem 153941
DrugBank APRD00948
Chemical data
Formula C12H15N5O3 
Mol. mass 277.279 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 13%
Metabolism  ?
Half life 128–149 hours
Excretion Renal 62–73%
Therapeutic considerations
Licence data


Pregnancy cat.


Legal status


Routes Oral

Entecavir (INN) (pronounced /ɛnˈtɛkəvɪr/) is an oral antiviral drug used in the treatment of hepatitis B infection. It is marketed under the trade name Baraclude (BMS).

Entecavir is a guanine analogue that inhibits all three steps in the viral replication process, and the manufacturer claims that it is more efficacious than previous agents used to treat hepatitis B (lamivudine and adefovir). It was approved by the U.S. Food and Drug Administration (FDA) in March 2005.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Entecavir". A list of authors is available in Wikipedia.
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