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Erlenmeyer-Plöchl azlactone and amino acid synthesis
The Erlenmeyer-Plochl azlactone and amino acid synthesis, named after Friedrich Gustav Carl Emil Erlenmeyer who partly discovered the reaction, is a series of chemical reactions which transform glycine to various other amino acids via an oxazolone and an azlactone.
Additional recommended knowledge
Hippuric acid self-condenses in the presence of acetic anhydride to 2-phenyl-oxazolone. This intermediate also has two acidic protons and reacts with benzaldehyde, acetic anhydride and sodium acetate to a so-called azlactone. This compound on reduction gives access to phenylalanine.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Erlenmeyer-Plöchl_azlactone_and_amino_acid_synthesis". A list of authors is available in Wikipedia.