To use all functions of this page, please activate cookies in your browser.
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
Flavin-containing monooxygenase system
The Flavin-containing monooxygenase (FMO) system is used for oxidation reactions in drug metabolism. The major difference between this system and the Cytochrome P450 monooxygenase system is that the FMO system does not act to oxidize carbon atoms. Also in contrast to P450, the FMO system is not induced by exposure to drugs or environmental pollutants.
Additional recommended knowledge
The FMO system is distinct from the cytrochrome P450 system in that it is non-inducible, does not have a heme prosthetic group but both require NADPH and oxygen; multiple isozymes are known for both; and they are both localized in microsomes of the endoplasmic reticulum.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Flavin-containing_monooxygenase_system". A list of authors is available in Wikipedia.|