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Fosmidomycin



Fosmidomycin
Systematic (IUPAC) name
3-[FORMYL(HYDROXY)AMINO]PROPYLPHOSPHONIC ACID
Identifiers
CAS number 66508-53-0
ATC code  ?
PubChem 572
DrugBank EXPT01469
Chemical data
Formula C4H10NO5P 
Mol. mass 183.100 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

Fosmidomycin is an antibiotic that specific inhibits DXP reductoisomerase, a key enzyme in the non-mevalonate pathway. It is a structural analogue of 2-C-methyl-D-erythrose 4-phosphate. It inhibits the E. coli enzyme with a KI value of 38 nM (4).

See also
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fosmidomycin". A list of authors is available in Wikipedia.
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