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Fosfomycin



Fosfomycin
Systematic (IUPAC) name
[(2R,3S)-3-methyloxiran-2-yl]phosphonic acid
Identifiers
CAS number 23155-02-4
78964-85-9 (tromethamine)
ATC code J01XX01
PubChem 446987
DrugBank APRD00987
Chemical data
Formula C3H7O4P 
Mol. mass 138.059 g/mol
Pharmacokinetic data
Bioavailability 30–37% (oral, fosfomycin tromethamine); varies with food intake
Protein binding Nil
Metabolism Nil
Half life 5.7 hours (mean)
Excretion Renal and fecal, unchanged
Therapeutic considerations
Pregnancy cat.

B(US)

Legal status

-only(US)

Routes Oral

Fosfomycin (also known as phosphomycin and phosphonomycin) is a broad-spectrum antibiotic produced by certain Streptomyces species. It is indicated in the treatment of urinary tract infections. It is usually administered as fosfomycin tromethamine, trade name Monurol.

Additional recommended knowledge

Fosfomycin is usually administered as a single dose.

See also


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fosfomycin". A list of authors is available in Wikipedia.
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