My watch list
my.chemeurope.com  
Login  

Spectinomycin



Spectinomycin
Systematic (IUPAC) name
(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-
4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)
decahydro-4H-pyrano[2,3-b][1,4]benzodioxin-4-one
Identifiers
CAS number 1695-77-8
ATC code J01XX04
PubChem 15541
DrugBank APRD01232
Chemical data
Formula C14H24N2O7 
Mol. mass 332.35 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

B(US)

Legal status
Routes  ?

Spectinomycin (marketed as the hydrochloride salt spectinomycin hydrochloride under the trade name Trobicin) is an aminocyclitol antibiotic produced by the bacterium Streptomyces spectabilis.

Additional recommended knowledge

Mechanism

It binds to the 30S ribosomal subunit in invading bacteria and interrupts protein synthesis.

Uses

It is given by injection to treat gonorrhea, especially in patients who are allergic to penicillins.

Side effects

Side effects include itching, chills, stomach-ash, and red rash.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Spectinomycin". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE