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Additional recommended knowledge
Beta globin (HBB, β-globin) is a protein that, along with alpha globin (HBA), makes up the most common form of hemoglobin in adult humans. The gene is located in the β-globin locus. Mutant beta globin is responsible for the sickling of red blood cells seen in sickle cell anemia. Expression of beta globin and the neighboring globins in the β-globin locus is controlled by single locus control region (LCR).
Human β-globin locus
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HBB". A list of authors is available in Wikipedia.|