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HLA-DM is an intracellular protein involved in peptide presentation by MHC class II. It is encoded by the genes HLA-DMA and HLA-DMB. HLA-DM functions by promoting the dissociation of the CLIP peptide (a place holder peptide) from MHC class II, and stabilizes MHC class II allowing exogenous peptides to bind.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "HLA-DM". A list of authors is available in Wikipedia.
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