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After the first step, a quaternary ammonium iodide salt is created as can be seen in the exact reaction mechanism in Figure 2. The major alkene product is the least substituted and generally the least stable, an observation known as the Hofmann rule. This is in direct contrast to normal elimination reactions where the more substituted, stable product is dominant (Zaitsev's rule).
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Hofmann_elimination". A list of authors is available in Wikipedia.|