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CYP27A1is a gene associated with cerebrotendineous xanthomatosis. It encodes a cytochrome P450 oxidase that is commonly known as sterol 27-hydroxylase, an enzyme involved in the biosynthesis of bile acids. The enzyme participates in the degradation of cholesterol to bile acids in both the classic and acidic pathways. In fact, it is initiating the acidic pathway by yielding oxysterols by introducing a hydroxylgroup to the carbon at 27 position in cholesterol.
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|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "CYP27A1". A list of authors is available in Wikipedia.|