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Lactam



  A lactam (the noun is a portmanteau of the words lactone + amide) is a cyclic amide. Prefixes may indicate the ring size: β-lactam (4-membered), γ-lactam (5-membered), δ-lactam (6-membered ring). That order in the nomenclature is because beta β, gamma γ and delta δ are the second, third and fourth letters in the alphabetical order of the Greek alphabet, respectively.

Additional recommended knowledge

Contents

Synthesis

General synthetic methods exist for the organic synthesis of lactams.

  • Lactams form by copper catalyzed 1,3-dipolar cycloaddition of alkynes and nitrones in the Kinugasa reaction

Reactions

See also

References

  1. ^ Spencer Knapp, Frank S. Gibson Organic Syntheses, Coll. Vol. 9, p.516 (1998); Vol. 70, p.101 (1992) Online article
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lactam". A list of authors is available in Wikipedia.
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