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Large-conductance mechanosensitive channel
Mechanosensitive ion channels (MscL) play a critical role in transducing physical stresses at the cell membrane into an electrochemical response.
Additional recommended knowledge
MscL forms a channel organized as a homopentamer, with each subunit containing two transmembrane α-helices. Prokaryotes harbor a large-conductance mechanosensitive channel (gene mscL) that opens in response to stretch forces in the lipid bilayer and participate in the regulation of osmotic pressure within the cell.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Large-conductance_mechanosensitive_channel". A list of authors is available in Wikipedia.|