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Lidoflazine



Lidoflazine
Systematic (IUPAC) name
2-[4-[4,4-bis(4-fluorophenyl)butyl]piperazin-1-yl]-N-(2,6-dimethylphenyl)acetamide
Identifiers
CAS number 3416-26-0
ATC code C08EX01
PubChem 3926
Chemical data
Formula C30H35F2N3O 
Mol. mass 491.615
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Therapeutic considerations
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Lidoflazine is a piperazine calcium channel blocker. It is a coronary vasodilator with some antiarrhythmic action. Lidoflazine was discovered at Janssen Pharmaceutica in 1964.

Additional recommended knowledge

References

  • Schaper WK, Xhonneux R, Jageneau AH., Stimulation of the coronary collateral circulation by lidoflazine (R 7904), Naunyn Schmiedebergs Arch Exp Pathol Pharmakol. 1965 Nov 4;252(1):1-8.
  • Schaper WK, Xhoneux R, Jageneau AH, Janssen PA., The cardiovascular pharmacology of lidoflazine, a long-acting coronary vasodilator, J Pharmacol Exp Ther. 1966 May;152(2):265-74.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Lidoflazine". A list of authors is available in Wikipedia.
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