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Myotubularin domain represents a region within eukaryotic myotubularin-related proteins that is sometimes found with IPR004182. Myotubularin is a dual-specific lipid phosphatase that dephosphorylates phosphatidylinositol 3-phosphate and phosphatidylinositol (3,5)-bi-phosphate. Mutations in gene encoding myotubularin-related proteins have been associated with disease.
Additional recommended knowledge
Human proteins containing this domain
MTM1; MTMR1; MTMR10; MTMR11; MTMR12; MTMR2; MTMR3; MTMR4; MTMR6; MTMR7; MTMR8; MTMR9; SBF1; SBF2;
This article includes text from the public domain Pfam and InterPro IPR010569
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Myotubularin". A list of authors is available in Wikipedia.|