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Systematic (IUPAC) name
CAS number 27848-84-6
ATC code C04AE02
PubChem 34040
DrugBank APRD00617
Chemical data
Formula C24H26BrN3O3 
Mol. mass 484.386 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Nicergoline is an ergoloid mesylate derivative used to treat senile dementia and other disorders with vascular origins. It has been found to increase mental agility and enhance clarity and perception. It decreases vascular resistance and increases arterial blood flow in the brain, improving the utilization of oxygen and glucose by brain cells. It has similar vasoactive properties in other areas of the body, particularly the lungs.

It is used for vascular disorders such as cerebral thrombosis and atherosclerosis, arterial blockages in the limbs, Raynaud's disease, vascular migraines, and retinopathy.

It is marketed under the trade name Sermion.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nicergoline". A list of authors is available in Wikipedia.
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