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Non-stop decay

Non-stop decay is a recently identified cellular mechanism of mRNA surveillance to detect mRNA molecules lacking a stop codon and prevent these mRNAs from translation. The non-stop decay pathway releases ribosomes that have reach the far 3' end of a mRNA and guides the mRNA to the exosome complex for degradation. [1]

See also


  1. ^ Vasudevan et al. (2002). "Non-stop decay--a new mRNA surveillance pathway". Bioessays 24: 785-8. PMID 12210514.
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Non-stop_decay". A list of authors is available in Wikipedia.
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