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CAS number 2226-71-3
PubChem 987
MeSH phosphopantetheine
Molecular formula C11H23N2O7PS
Molar mass 358.349 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

4'-Phosphopantetheine is an essential prosthetic group of acyl carrier protein (ACP) and peptidyl carrier proteins (PCP) and aryl carrier proteins (ArCP) derived from Coenzyme A.


Phosphopantetheine fulfils two demands.

  • Firstly, the intermediates remain covalently linked to the synthases (or synthetases) in an energy-rich thiol ester linkage.
  • Secondly, the flexibility and length of phosphopantetheine chain (approximately 2 nm) allows the covalently tethered intermediates to have access to spatially distinct enzyme active sites.

See also

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This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phosphopantetheine". A list of authors is available in Wikipedia.
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