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Phosphopantetheine



Phosphopantetheine
Identifiers
CAS number 2226-71-3
PubChem 987
MeSH phosphopantetheine
Properties
Molecular formula C11H23N2O7PS
Molar mass 358.349 g/mol
Except where noted otherwise, data are given for
materials in their standard state
(at 25 °C, 100 kPa)

Infobox disclaimer and references

4'-Phosphopantetheine is an essential prosthetic group of acyl carrier protein (ACP) and peptidyl carrier proteins (PCP) and aryl carrier proteins (ArCP) derived from Coenzyme A.

Additional recommended knowledge

Functions

Phosphopantetheine fulfils two demands.

  • Firstly, the intermediates remain covalently linked to the synthases (or synthetases) in an energy-rich thiol ester linkage.
  • Secondly, the flexibility and length of phosphopantetheine chain (approximately 2 nm) allows the covalently tethered intermediates to have access to spatially distinct enzyme active sites.

See also

This metabolism related compound article is a stub. You can help Wikipedia by expanding it.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Phosphopantetheine". A list of authors is available in Wikipedia.
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