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Poly vinyl pyrrolidone
PVP (polyvinyl pyrrolidone, povidone, polyvidone) is a water-soluble polymer made from the monomer N-vinyl pyrrolidone:
Additional recommended knowledge
Registry Numbers and Synonyms
CAS Number: 9003-39-8
Molecular Formula: C6H9NO
Merck 13, 7783
1-Ethenyl-2-pyrrolidoinone homopolymer (IUPAC); Poly[1-(2-oxo-1-pyrrolidinyl)ethylene]; polyvidone; polyvinylpyrrolidone; PVP; 1-vinyl-2-pyrrolidinone polymer
PVP is soluble in water and other polar solvents. In water it has the useful property of Newtonian viscosity. When dry it is a light flaky powder, which readily absorbs up to 18% of its weight in atmospheric water. In solution, it has excellent wetting properties and readily forms films. This makes it good as a coating or an additive to coatings.
The monomer is carcinogenic and is extremely toxic to aquatic life. However the polymer PVP in its pure form is so safe that not only is it edible by humans, but it was used as a blood plasma expander for trauma victims after the first half of 20th century.[clarify]
It is used as a binder in many pharmaceutical tablets; being completely inert to humans, it simply passes through the body. PVP added to Iodine forms a complex; in solution it is known under the trade name Betadine.
PVP binds to polar molecules exceptionally well, owing to its polarity. This has led to its application in coatings for photo-quality ink-jet papers and transparencies, as well as in inks for inkjet printers.
PVP is also used in personal care products, such as shampoos and toothpastes, in paints, and adhesives that you have to moisten, such as old-style postage stamps and envelopes. It has also been used in contact lens solutions and in steel-quenching solutions. PVP is the basis of the early formulas for hair sprays and hair gels, and still continues to be a component of some.
As a food additive, PVP is a stabilizer and has E number E1201. PVPP is E1202. It is also used in the wine industry as a fining agent for white wine. Such white wine is not suitable for vegans, as PVPP is a dairy derivative..
In molecular biology, PVP can be used as a blocking agent during Southern blot analysis as a component of Denhardt's buffer. It is also exceptionally good at adsorbing polyphenols during DNA purification. Polyphenols are common in many plant tissues and can deactivate proteins if not removed and therefore inhibit many downstream reactions like PCR.
PVP is also used in many technical applications:
Material Safety Data Sheet
MSDS for PVP from EMD Chemicals
A cross-linked form of PVP is also used as a disintegrant in pharmaceutical tablets. 1 cross linked polyvinyl pyrrolidone (PVPP) - is used to bind impurities to remove them from solutions. Basically, PVPP is a more highly cross-linked version of PVP, which makes it insoluble in water. This means that it can be used as a fining to extract impurities (via agglomeration followed by filtration). Similarly PVPP can also be taken as a tablet to absorb compounds causing diarrhoea. (Cf. bone char, charcoal.)
Categories: Vinyl polymers | Pyrrolidones
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Poly_vinyl_pyrrolidone". A list of authors is available in Wikipedia.|