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Quinuclidine is an organic compound and a bicyclic amine and used as a catalyst and a chemical building block. It is a strong base with pKa of the conjugate acid of 19.5 ranking it between triethylamine (18.5) and DBN (23.8). This is due to greater availability of the nitrogen lone pair. It can be prepared by reduction of quinuclidone.
Additional recommended knowledge
The compound is structurally related to DABCO in which the other bridgehead is also nitrogen and tropane with a slightly different carbon frame.
A biomolecule with the quinuclidine framework is quinine.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Quinuclidine". A list of authors is available in Wikipedia.|