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RANK (Receptor Activator of Nuclear Factor κ B), also known as TRANCE Receptor, is a type I membrane protein which is expressed on the surface of osteoclasts and is involved in the activation of osteoclasts upon ligand binding. It is also expressed on dendritic cells and facilitates immune signaling. RANK ligand is found on the surface of stromal cells, osteoblasts, and T cells.
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|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "RANK". A list of authors is available in Wikipedia.|