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In plants, raspberry ketone is synthesized from coumaroyl-CoA. But since the natural abundance of raspberry ketone is very low, it is prepared industrially by a variety of methods from chemical intermediates.
When given to mice in high doses (up to 2% of food intake), raspberry ketone has been shown to prevent high-fat-diet-induced elevations in body weight. This effect is reported to stem from the alteration of lipid metabolism, increasing norepinephrine-induced lipolysis. Although products containing this compound are marketed for weight loss, this effect has not been demonstrated in humans.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Raspberry_ketone". A list of authors is available in Wikipedia.