To use all functions of this page, please activate cookies in your browser.
With an accout for my.chemeurope.com you can always see everything at a glance – and you can configure your own website and individual newsletter.
- My watch list
- My saved searches
- My saved topics
- My newsletter
S-Nitroso-N-acetylpenicillamine is the chemical compound with the formula ONSC(CH3)2CH(NHAc)CO2H (Ac = acetyl). The molecule is an important donor of the NO+ in biochemistry. It has received much attention because nitric oxide and some organic nitroso derivatives serve as signaling molecules in living systems, especially related to vasodilation. SNAP is used as a model for the general class of S-nitrosothiols. S-Nitrosoglutathione is a related agent.
Additional recommended knowledge
Organic chemistry background
Thionitroso compounds arise from condensation from nitrous acid and a thiol:
Many other methods exist for their synthesis. Once formed, these deeply coloured compounds are often thermally unstable with respect to formation of the disulfide and nitric oxide.
SNAP releases NO+ upon treatment with acids:
Thionitroso compounds transfer NO to other thiols:
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "S-Nitroso-N-acetylpenicillamine". A list of authors is available in Wikipedia.|