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Selective Relaxant Binding Agent
Additional recommended knowledge
Discovery of SRBAs
The discovery of SRBA as a new class of drug is the result of work done at Organon laboratories in Scotland. Cyclodextrins were explored as a means to solubilize rocuronium bromide (a steroidal NMBA) in a neutral aqueous solution. Upon creating numerous modified cyclodextrins, one particular molecule was found to possess extremely high affinity for the rocuronium molecule. Originally known as Org25969, it is now generically named sugammadex sodium.
|This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Selective_Relaxant_Binding_Agent". A list of authors is available in Wikipedia.|