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Systematic (IUPAC) name
CAS number 14636-12-5
ATC code H01BA04
PubChem 72081
DrugBank EXPT03310
Chemical data
Formula C52H74N16O15S2 
Mol. mass 1227.37 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding ~30%
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes IV

Terlipressin is an analogue of vasopressin used as a vasoactive drug in the management of hypotension. It has been found to be effective when norepinephrine does not help.

Indications for use include norepinephrine-resistant septic shock[1] and hepatorenal syndrome.[2] In addition, it is used in bleeding esophageal varices.[3]

Terlipressin is marketed under the brand name Glypressin (Ferring Pharmaceuticals).

See also


  1. ^ O'Brien A, Clapp L, Singer M (2002). "Terlipressin for norepinephrine-resistant septic shock". Lancet 359 (9313): 1209–10. PMID 11955542.
  2. ^ Uriz J, Ginès P, Cárdenas A, Sort P, Jiménez W, Salmerón J, Bataller R, Mas A, Navasa M, Arroyo V, Rodés J (2000). "Terlipressin plus albumin infusion: an effective and safe therapy of hepatorenal syndrome". J Hepatol 33 (1): 43–8. PMID 10905585.
  3. ^ Ioannou G, Doust J, Rockey D. "Terlipressin for acute esophageal variceal hemorrhage". Cochrane Database Syst Rev: CD002147. PMID 12535432.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Terlipressin". A list of authors is available in Wikipedia.
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