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Mangafodipir


Mangafodipir
Systematic (IUPAC) name
?
Identifiers
CAS number	119797-12-5
ATC code	V08CA05
PubChem	107732
Chemical data
Formula	C₂₂H₂₈Mn N₄O₁₄P₂
Mol. mass	689.362 g/mol
Pharmacokinetic data
Bioavailability	NA
Protein binding	27% (manganese) Negligible (DPDP)
Metabolism	?
Half life	20 minutes (manganese) 50 minutes (DPDP)
Excretion	Renal and fecal (manganese) Renal (DPDP)
Therapeutic considerations
Pregnancy cat.	Not to be used
Legal status
Routes	Intravenous infusion

Mangafodipir (sold under the brand name Teslascan as mangafodipir trisodium) is a contrast agent delivered intravenously to enhance contrast in magnetic resonance imaging (MRI) of the liver. It has two parts, paramagnetic manganese (II) ions and the chelating agent fodipir (dipyridoxyl diphosphate, DPDP). Normal liver tissue absorbs the manganese more than abnormal or cancerous tissue. The manganese shortens the longitudinal relaxation time (T1), making the normal tissue appear brighter in MRIs. This enhanced contrast allows lesions to be more easily identified.