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Tiopronin



Tiopronin
Systematic (IUPAC) name
[(2-mercaptopropanoyl)amino]acetic acid
Identifiers
CAS number 1953-2-2
ATC code R05CB12
PubChem 5483
Chemical data
Formula C5H9NO3S 
Mol. mass 163.196 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

C(US)

Legal status

-only(US)

Routes  ?

Tiopronin (trade name Thiola) is a prescription thiol drug used to control the rate of cystine solidification and excretion in the disease cystinuria. It is a white crystalline powder. Due to its rarity, it falls under the classification of "orphan drug".

Additional recommended knowledge

Contents

Side effects

Tiopronin may present a wide variety of side effects, but side effects are usually limited and subside over time with continued usage. With the rarity of the disease, tiopronin has not been studied substantially, with an extremely low percentage of individuals available for testing.

Other uses

Tiopronin is used primarily for cystinuria and is well known in the cystinuric community. It may also be used for Wilson's disease (an overload of copper in the body), and certain types of rare arthritis. It should be mentioned though, that tiopronin is not an anti-inflammatory.


Depending on the severity of a person's cystinuria, tiopronin may be taken for life, possibly starting in early childhood.

See also

References

  • Thiola Main Site
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Tiopronin". A list of authors is available in Wikipedia.
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