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Trans-splicing is a special form of RNA processing in eukaryotes where exons from two different primary RNA transcripts are joined end to end and ligated.

In contrast "normal" (cis-)splicing processes a single molecule. That is, trans-splicing results in a RNA transcript that came from multiple RNA polymerases on the genome.


  • Dixon RJ, Eperon IC, Samani NJ (2007). "Complementary intron sequence motifs associated with human exon repetition: a role for intragenic, inter-transcript interactions in gene expression". Bioinformatics 23 (2): 150-5. doi:10.1093/bioinformatics/btl575. PMID 17105720.
  • Yang Y, Walsh CE (2005). "Spliceosome-mediated RNA trans-splicing". Mol. Ther. 12 (6): 1006-12. doi:10.1016/j.ymthe.2005.09.006. PMID 16226059.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Trans-splicing". A list of authors is available in Wikipedia.
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