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Trilostane



Trilostane
Systematic (IUPAC) name
 ?
Identifiers
CAS number 13647-35-3
ATC code H02CA01
PubChem 656583
DrugBank APRD01276
Chemical data
Formula C20H27NO3 
Mol. mass 329.433 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 8 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status

Withdrawn (U.S.)

Routes  ?

Trilostane is an inhibitor of 3 β-hydroxysteroid dehydrogenase used in the treatment of Cushing's syndrome.[1] It was withdrawn from the United States market in April 1994.

Additional recommended knowledge


References

  1. ^ Komanicky P, Spark RF, Melby JC. (1978). "Treatment of Cushing's syndrome with trilostane (WIN 24,540), an inhibitor of adrenal steroid biosynthesis". Journal of Clinical Endocrinology and Metabolism 47 (5): 1042–1051. PMID 233687. Retrieved on 2007-06-17.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Trilostane". A list of authors is available in Wikipedia.
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