My watch list
my.chemeurope.com  
Login  

Triamcinolone



Triamcinolone
Systematic (IUPAC) name
9-fluoro-11,16,17-trihydroxy-17- (2-hydroxyacetyl) -10,13-dimethyl-6,7,8,9,10,11,12, 13,14,15,16,17- dodecahydrocyclopenta[a]phenanthren-3-one
Identifiers
CAS number 124-94-7
ATC code A01AC01 D07AB09, D07XB02, H02AB08, R01AD11, R03BA06, S01BA05
PubChem 31307
DrugBank APRD00422
Chemical data
Formula C21H27FO6 
Mol. mass 394.434 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 68%
Metabolism Hepatic
Half life 88 minutes
Excretion Fecal and renal
Therapeutic considerations
Pregnancy cat.

A (Au), C (US)

Legal status

POM(UK) -only(US)

Routes Oral, topical, IM, intra-articular, intrasynovial

Triamcinolone (trade names Kenalog, Aristocort, Nasacort, Tri-Nasal, Triderm, Azmacort, Trilone, Volon A, Tristoject, Fougera;) is a synthetic corticosteroid given orally, by injection, inhalation, or as a topical ointment or cream.

Additional recommended knowledge

Uses

They are also used in the post-operative period of certain cosmetic surgery procedures, notably rhinoplasty. Injected into the subcutaneous area, they may help to alleviate stubborn swelling and decrease the presence of scar tissue.

Topical triamcinolone acetonide paste is often prescribed for mouth or gum irritation following dental procedures.

Triamcinolone is occasionally used to treat severe cases of hayfever.[1]

Forms

Different triamcinolone salts are available, including acetonide, hexacetonide and diacetate.

Triamcinolone acetonide is a more potent type of triamcinolone, being about 8 times as effective as prednisone.

References

  1. ^ Hayfever (allergic rhinitis) - BUPA


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Triamcinolone". A list of authors is available in Wikipedia.
Your browser is not current. Microsoft Internet Explorer 6.0 does not support some functions on Chemie.DE