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Fluocinolone acetonide

Fluocinolone acetonide
Systematic (IUPAC) name
CAS number 67-73-2
ATC code C05AA10 D07AC04
PubChem 6215
DrugBank APRD00977
Chemical data
Formula C24H30F2O6 
Mol. mass 452.488 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism Hepatic, CYP3A4-mediated
Half life 1.3 to 1.7 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes Topical

Fluocinolone acetonide is a corticosteroid primarily used in dermatology to reduce skin inflammation and relieve itching. It is a synthetic hydrocortisone derivative. The fluorine substitution at position 9 in the steroid nucleus greatly enhances its activity. A typical dosage strength used in dermatology is 0.01–0.025%. One such cream is sold under the brand name Flucort-N and includes the antibiotic neomycin.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Fluocinolone_acetonide". A list of authors is available in Wikipedia.
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