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Levocabastine



Levocabastine
Systematic (IUPAC) name
1-[4-cyano-4-(4-fluorophenyl)-cyclohexyl]- 3-methyl-4-phenyl-piperidine-4- carboxylic acid
Identifiers
CAS number 79516-68-0
ATC code R01AC02 S01GX02
PubChem 54385
DrugBank APRD01069
Chemical data
Formula C26H29FN2O2 
Mol. mass 420.519 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3
Excretion  ?
Therapeutic considerations
Pregnancy cat.

B3(AU) C(US)

Legal status

Prescription only

Routes Ophthalmic, intranasal[1]

Levocabastine is a selective second-generation H1-receptor antagonist used for allergic conjunctivitis.

Additional recommended knowledge

Levocabastine was discovered at Janssen Pharmaceutica in 1979.

References

  • Pipkorn U, Bende M, Hedner J, Hedner T., A double-blind evaluation of topical levocabastine, a new specific H1 antagonist in patients with allergic conjunctivitis, Allergy. 1985 Oct;40(7):491-6.
  • RxList (2004). Livostin Online, Description, Chemistry, Ingredients - Levocabastine. LIVOSTIN. RxList Inc. Retrieved on 9 October, 2005.
  • Novartis Pharmaceuticals (March 2002). LIVOSTIN® (PDF). Retrieved on August 20, 2006.
  1. ^  RxMed: Pharmaceutical Information - LIVOSTIN NASAL SPRAY. Retrieved on 13 November, 2005.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Levocabastine". A list of authors is available in Wikipedia.
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