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Nedocromil



Nedocromil
Systematic (IUPAC) name
9-ethyl-4,6-dioxo-10-propyl-6,9-dihydro-
4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid
Identifiers
CAS number 69049-73-6
ATC code R01AC07 R03BC03, S01GX04
PubChem 50294
DrugBank APRD01137
Chemical data
Formula C19H17NO7 
Mol. mass 371.341 g/mol
Pharmacokinetic data
Bioavailability  ?
Protein binding 89%
Metabolism not metabolized
Half life ~3.3 hours
Excretion excreted unchanged
Therapeutic considerations
Pregnancy cat.

?

Legal status

POM(UK)

Routes Inhalation and eye drops

Nedocromil sodium is a medication used to prevent wheezing, shortness of breath, and other breathing problems caused by asthma. It is administered by an inhaler under the brand name Tilade.

Additional recommended knowledge

Nedocromil is classified as a cromone. Nedocromil acts as a mast cell stabilizer, inhibits the degranulation of mast cells, prevents release of histamine and tryptase, so preventing the synthesis of prostaglandins and leukotrienes.

 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nedocromil". A list of authors is available in Wikipedia.
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