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Systematic (IUPAC) name
dihydrodibenzo[b,e]oxepin-2-yl}acetic acid
CAS number 113806-05-6
ATC code S01GX09 R01AC08
PubChem 5281071
DrugBank APRD00310
Chemical data
Formula C21H23NO3 
Mol. mass 337.412 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life 3 hours
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes Ophthalmic

Olopatadine hydrochloride is an antihistamine and mast cell stabilizer, sold as a prescription eye drop (0.2% solution, trademark Pataday (or Patanol S in some countries), manufactured by Alcon). It is used to treat itching associated with allergic conjunctivitis (eye allergies). Olopatadine hydrochloride 0.1% is sold as trademark Patanol (or Opatanol in some countries).

It should not be used to treat irritation caused by contact lenses. The usual dose for trademark Pataday is 1 drop in each affected eye once a day. The usual dose for trademark Patanol is 1 drop in each affected eye 2 times per day, with 6 to 8 hours between doses.

Its side effects may include headaches (7% of occurrence) burning and stinging (5%), dry eye, foreign body sensation, hyperemia, keratitis, lid edema, pruritus, asthenia, cold syndrome, pharyngitis, rhinitis, sinusitis, and taste change.

This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Olopatadine". A list of authors is available in Wikipedia.
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