Tuaminoheptane (or tuamine) is a nasal decongestant drug which is a sympathomimeticstimulant and vasoconstrictor. However it can cause skin irritation, which limits its usefulness as a nasal decongestant. Side effects can include acute glaucoma, tachycardia and hypertension.
^ Delicado EG, Fideu MD, Miras-Portugal MT, Pourrias B, Aunis D. Effect of tuamine, heptaminol and two analogues on uptake and release of catecholamines in cultured chromaffin cells. Biochemical Pharmacology. 1990 Aug 15;40(4):821-5.
^ Raoux M, Colomban C, Delmas P, Crest M. The amine-containing cutaneous irritant heptylamine inhibits the volume-regulated anion channel and mobilizes intracellular calcium in normal human epidermal keratinocytes. Molecular Pharmacology. 2007 Jun;71(6):1685-94.