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Systematic (IUPAC) name
CAS number 86939-10-8
ATC code  ?
PubChem 126280
Chemical data
Formula C16H15Cl2N 
Mol. mass 292.202 g/mol
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.


Legal status
Routes  ?

Indatraline, also known as Lu 19-005, is a nonselective monoamine reuptake inhibitor that has been shown to block the reuptake of dopamine, norepinephrine, and serotonin with effects similar to those of cocaine. However, the effects have been shown to have slower onset and longer duration than cocaine, suggesting that the compound may, along with similar compounds, be used for treatment of cocaine abuse.[1] Research has also suggested that indatraline can be used to block the action of methamphetamine.[2]

For a more detailed discussion of indatraline pharmacology, see Indatraline pharmacology


  1. ^ Negus SS, Brandt MR, Mello NK. "Effects of the long-acting monoamine reuptake inhibitor indatraline on cocaine self-administration in rhesus monkeys." J Pharmacol Exp Ther (1999) 291(1):60-9.[1]
  2. ^ Rothman, B. R. eta al, "Neurochemical Neutralization of Methamphetamine With High-Affinity Nonselective Inhibitors of Biogenic Amine Transporters: A Pharmacological Strategy for Treating Stimulant Abuse." Synapse (2000) 35:222-227.[2]
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Indatraline". A list of authors is available in Wikipedia.
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