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Brasofensine



Brasofensine
Systematic (IUPAC) name
1-[(2R,3S)-3-(3,4-dichlorophenyl)-8-methyl -8-azabicyclo[3.2.1]octan-2-yl]-N-methoxymethanimine
Identifiers
CAS number 171655-91-7
ATC code  ?
PubChem 9554198
Chemical data
Formula C16H20Cl2N2O 
Mol. mass 327.248 g/mol
SMILES search in eMolecules, PubChem
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status

Legal

Routes  ?


Brasofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor. It has been researched for the treatment of Parkinson's Disease, depression and treatment of drug dependence. Phase II trials were conducted in 1996 and brasofensine was shown to be well tolerated at a dose of 4mg, but the current progress of this drug is unknown.[1][1]

Additional recommended knowledge

See also Tesofensine


References

  1. ^ Frackiewicz EJ, Jhee SS, Shiovitz TM, Webster J, Topham C, Dockens RC, Whigan D, Salazar DE, Cutler NR. Brasofensine treatment for Parkinson's disease in combination with levodopa/carbidopa. Ann Pharmacother. 2002 Feb;36(2):225-30.
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Brasofensine". A list of authors is available in Wikipedia.
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