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GYKI-52895



GYKI-52895
Systematic (IUPAC) name
4-(8,9-Dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine
Identifiers
CAS number 869360-93-0
ATC code  ?
PubChem 3539
Chemical data
Formula C17H17N3O2 
Mol. mass 295.34
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

?

Legal status
Routes  ?

GYKI-52895 is a drug which is a 2,3-benzodiazepine derivative. Unlike other similar drugs, GYKI-52895 is a selective dopamine reuptake inhibitor,[1][2] which presumably would produce stimulant effects in vivo.


References

  1. ^ Horváth K, Szabó H, Pátfalusi M, Berzsenyi P, Andrási F. Pharmacological Effects of GYKI 52895, a New Selective Dopamine Uptake Inhibitor. European Journal of Pharmacology. 1990; 183(4):1416-1417.
  2. ^ Huang CL, Chen HC, Huang NK, Yang DM, Kao LS, Chen JC, Lai HL, Chern Y. Modulation of Dopamine Transporter Activity by Nicotinic Acetylcholine Receptors and Membrane Depolarization in Rat Pheochromocytoma PC12 Cells. Journal of Neurochemistry. 1999; 72(6): 2437–2444.

US Patent 6638928

v • d • e
Benzodiazepines (N05BA, N05CD)
1,4-Benzodiazepines
Triazolobenzodiazepines
Imidazobenzodiazepines
Oxazolobenzodiazepines
ThienobenzodiazepinesBrotizolam • Clotiazepam • Etizolam
1,5-BenzodiazepinesArfendazam • Clobazam • Lofendazam • Triflubazam
2,3-BenzodiazepinesGirisopam • GYKI-52895 • Nerisopam • Tofisopam
Benzodiazepine ProdrugsAvizafone • Rilmazafone
OthersBentazepam • Ketazolam • Tifluadom • Zolazepam
v • d • e
Stimulants
EugeroicsAdrafinil • Armodafinil • Carphedon • Modafinil
Phenethylamines

4-Fluoroamphetamine • 4-Fluoromethamphetamine • 4-Methylmethcathinone • 4-MTA • α-PPP • Amphechloral • Amphetamine (Dexamphetamine, Adderall) • Amphetaminil • Benzphetamine • Bupropion • Cathinone • Chlorphentermine • Clobenzorex • Clortermine • Cypenamine • Diethylpropion • Dimethoxyamphetamine • Dimethylamphetamine • Dimethylcathinone • Diphenyl prolinol • Ephedrine • Epinephrine • Ethcathinone • Ethylamphetamine • Fencamfamine • Fenethylline • Fenfluramine • Fenproporex • Feprosidnine • Furfenorex • Levomethamphetamine • Lisdexamfetamine • MDMA • Mefenorex • Methamphetamine • Methcathinone • Methoxyphedrine • Methylone • Octopamine • Parahydroxyamphetamine • PMA • PMEA • PMMA • PPAP • Phendimetrazine • Phenmetrazine • Phentermine • Phenylephrine • Phenylpropanolamine • Prolintane  Propylamphetamine • Pseudoephedrine • Selegiline • Synephrine • Xylopropamine

Piperazines

BZP • MeOPP • MBZP • mCPP • 2C-B-BZP

XanthinesCaffeine • Aminophylline • Paraxanthine • Theobromine • Theophylline
Tropanes

Brasofensine • CFT • Cocaethylene • Cocaine • Lometopane • RTI-121 • Tesofensine • Troparil

CholinergicsArecoline • Cotinine • Nicotine
ConvulsantsBicuculline • Gabazine • Pentetrazol • Picrotoxin • Strychnine • Thujone
Phenylaminooxazoles
Others
See also Sympathomimetic amines
 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "GYKI-52895". A list of authors is available in Wikipedia.
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