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Nerisopam



Nerisopam
Systematic (IUPAC) name
4-(7,8-dimethoxy-4-methyl-5H-2,3-benzodiazepin-1-yl)aniline
Identifiers
CAS number 102771-12-0
ATC code  ?
PubChem 65875
Chemical data
Formula C18H19N3O2 
Mol. mass 309.36
Pharmacokinetic data
Bioavailability  ?
Metabolism  ?
Half life  ?
Excretion  ?
Therapeutic considerations
Pregnancy cat.

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Legal status
Routes  ?

Nerisopam (GYKI-52322) is a drug which is a 2,3-benzodiazepine derivative, related to tofisopam. It has potent anxiolytic and neuroleptic effects in animal studies.[1][2][3]

Additional recommended knowledge


References

  1. ^ Horváth K, Andrási F, Berzsenyi P, Pátfalusi M, Patthy M, Szabó G, Sebestyén L, Bagdy E, Körösi J, Botka P. A new psychoactive 5H-2,3-benzodiazepine with a unique spectrum of activity. Arzneimittelforschung. 1989 Aug;39(8):894-9.
  2. ^ Horváth K, Andrási F, Botka P, Hámori T. Anxiolytic profile of girisopam and GYKI 52,322 (EGIS 6775). Comparison with chlordiazepoxide and buspirone. Acta Physiologica Hungarica. 1992;79(2):153-61.
  3. ^ Palkovits M, Baffi JS, Berzsenyi P, Horváth EJ. Anxiolytic homophthalazines increase Fos-like immunoreactivity in selected brain areas of the rat. European Journal of Pharmacology. 1997 Jul 16;331(1):53-63.


 
This article is licensed under the GNU Free Documentation License. It uses material from the Wikipedia article "Nerisopam". A list of authors is available in Wikipedia.
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